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Frequently asked questions

For further information, please consult the Patient Information Leaflet.


What is PLENVU®?

PLENVU® is a polyethylene glycol (PEG) laxative designed to cleanse your bowel prior to your planned colonoscopy.

What will happen when I take PLENVU®?

PLENVU® will cause you to have diarrhoea, which is meant to cleanse your bowel before you have your colonoscopy. A clean bowel will allow a clear view of the inner lining, which is important for accurate diagnosis and treatment.

Can I take other medications while I am taking PLENVU®?

Any medicines taken by mouth (orally) may not be absorbed in the usual way if taken within 1 hour of taking PLENVU®. Speak to your doctor, nurse or pharmacist if you are taking any other medicines (e.g. oral contraceptives).

What can I drink while I am taking PLENVU®?

Once you start taking PLENVU® you may only drink clear fluids. Suitable clear fluids include water, clear soups, herbal tea, black tea or coffee (without milk), soft drinks/diluted cordials (NOT blackcurrant) and clear fruit juices (without pulp). Do not drink alcohol, milk, anything coloured red or purple, or any other drinks containing pulp material.

You can drink clear fluids until 2 hours before a colonoscopy under general anaesthesia, or 1 hour before a colonoscopy without general anaesthesia.

Can I eat anything while I am taking PLENVU®?

No. After you start taking PLENVU® you should not eat any solid food until after your colonoscopy. However, it is important to drink clear fluids as directed and stay hydrated throughout the preparation.

Do I need to follow a special diet before taking PLENVU®?

Yes, you should eat light meals before taking PLENVU®. Please see the Taking PLENVU® page for what meals you should eat depending on your dosing schedule. Your healthcare professional can also advise you on what you can and can't eat.

Can I mix PLENVU® with any clear liquid?

PLENVU® should only be mixed with water. Refrigerating it once it has been made up may make it easier to take.

How will I know which dosing schedule to follow?

Your doctor, nurse or pharmacist should tell you this when they schedule your colonoscopy and prescribe PLENVU®. If they have not told you, please contact them to confirm this.

Do I have to drink the full dose of PLENVU®?

Yes, you must drink the full dose of PLENVU®, including the additional clear fluids. If you do not drink the full dose of PLENVU® then your bowel may not be cleaned effectively. This may lead to the colonoscopy having to be cancelled and repeated.

PLENVU® is taking a long time to dissolve. Can I drink it before it has all dissolved?

No, please keep stirring or mixing until it is completely dissolved. This may take several minutes.

I feel sick. What should I do?

Try drinking more slowly, or you can take a short break from drinking PLENVU®. Continue to drink PLENVU® when the feeling has subsided.

How long will the colonoscopy take?

The colonoscopy should take around 35 to 40 minutes to complete. You will then be in the recovery ward for up to approximately 2 hours afterwards.

I am diabetic. What should I do about my medication?

Talk to your doctor, and they will advise you how to manage your medication leading up to your colonoscopy and after it.

Why can't I drink or consume anything red or purple while taking PLENVU®?

Drinking red- or purple-coloured fluids can reduce the accuracy of the colonoscopy. This is because they can stain the bowel or look like small amounts of blood.

I am very thin. Do I have to take the full dose of PLENVU®?

Yes. You must follow the instructions given to you. Your bowel is approximately 1.8 meters (6 feet) long and must be completely emptied to help ensure an accurate and thorough examination.

I seem to be all cleaned out but I haven't finished the full dose of PLENVU®. Do I have to finish it?

Yes. You must follow the instructions given to you. Your bowel is approximately 1.8 meters (6 feet) long and must be completely emptied to help ensure an accurate and thorough examination.

Can I use a cream to prevent a sore bottom?

Yes, you may find it helpful to use a barrier cream, such as petroleum jelly.

I have started taking PLENVU® but I haven't had a bowel movement yet. What should I do?

Some people have a bowel movement immediately after starting taking PLENVU® and for others it may take longer. Continue taking PLENVU® as instructed. If you do not have a bowel movement within 6 hours of taking PLENVU® stop taking PLENVU® and contact your doctor immediately.

Can I have sugar in my tea/coffee or other clear fluids?

Yes, you can use sugar or sugar substitutes in any clear fluids.

Can I have milk in my tea/coffee?

No, do not consume any dairy products, including milk or cream.

Can I drink alcohol while taking PLENVU®?

No, as alcoholic drinks can cause dehydration.

Can I brush my teeth the morning of my procedure?

Yes, but please ensure you don’t swallow any toothpaste.

Can I have soup as one of my clear fluids?

You can only have clear soup. You may not have noodles, meat or vegetables.

Can I have a colonoscopy if I am having my menstrual period?

Yes.

Will the colonoscopy hurt?

You will be given sedation during the procedure to help keep you comfortable.

When can I eat after my colonoscopy?

Your doctor or nurse will advise you when you can eat and drink normally again after your colonoscopy although it may also depend on how you feel.

After the colonoscopy, when will I have a normal bowel movement?

It may take up to a week of eating solid food before you have a bowel movement.

Will I experience any side effects?

Like all medicines, PLENVU® can cause side effects, although not everybody gets them. However, it is normal to get diarrhoea when you take PLENVU®. Please refer to the Patient Information Leaflet for more information.

If you get any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in the patient information leaflet.

Adverse events should be reported to your national regulatory authority. Adverse events should also be reported directly to Norgine Ltd. Email: globalmedinfo@norgine.com

By reporting side effects, you can help provide more information on the safety of this medicine.

If you get any side effects, talk to your doctor, nurse or pharmacist. This includes any possible side effects not listed in the Patient Information Leaflet. Adverse events should be reported to your national regulatory authority. Adverse events should also be reported directly to Norgine Ltd. Email: globalmedinfo@norgine.com
By reporting side effects, you can help provide more information on the safety of this medicine.